Team
Dr. Zdeněk Kameník
Head of the Laboratory
After accomplishing my PhD. degree in Analytical Chemistry at the Charles University in Prague in 2012, I joined Greg Challis group at the University of Warwick in the UK as a postdoctoral researcher, investigating bottromycin biosynthesis. Then, I moved back to Prague and worked in the Jiri Janata group at the Institute of Microbiology Czech Acad Sci on the biosynthesis of bioactive metabolites produced by soil and marine Actinobacteria – lincosamides and pyrrolobenzodiazepines. In 2018, I participated in a metabolomics project at the University of California at San Diego, USA, in Pieter Dorrestein group. In 2020, I was awarded the Lumina Quaeruntur premium from Czech Acad Sci and established a team for microbial biosynthesis and metabolomics. My top achievements were published in top scientific journals including ACS Chemical Biology, Chemical Science, Journal of Chromatography A, Journal of the American Chemical Society (JACS), Nature Communications, Natural product Reports, and Scientific reports.
Dr. Jiří Janata
RESEARCHER
biotechnology and collaboration with private sector
biotechnology and collaboration with private sector
Dr. Lucie Najmanová
RESEARCHER
metagenome analysis, microbiome research
Dr. Stanislav Kadlčík
RESEARCHER
genome mining, biosynthesis
Dr. Markéta Koběrská
RESEARCHERgenetic manipulation
Dr. Radek Gažák
RESEARCHER
organic chemist
Dr. Lucie Zdvořáková
POSTDOCTORAL FELLOW
biosynthesis, structure of proteins
Dr. Aninda Mazumdar
POSTDOCTORAL FELLOW
metabolomics
Dr. Tommaso Stefani
POSTDOCTORAL FELLOW
metabolomics, analytical chemistry
Dr. Fanny Demay
POSTDOCTORAL FELLOW
Dr. Durga Mahor
POSTDOCTORAL FELLOW
Dr. Vojtěch Kovařovič
Bioinformatician
Dr. Lucie Trögelová
ASSOCIATE SCIENTIST
MSc. Julie Pokorná
LAB TECHNICIAN
MSc. Marie Vachulová
LAB TECHNICIAN
MSc. Natalia Slonská
LAB MANAGER
MSc. Anna Gažáková
LAB TECHNICIAN
- Mufarrah Mehboob FSUC-Exploring the Antibiotic-Responsive Regulatory function of ABCF Proteins in Antibiotic-Producing Bacteria (2023)
- Ondřej Hřebíček -FSUC – Development of bioinformatics software for targeted analysis of gene clusters, and its application to study the biosynthesis of bacterial metabolites with an unusual 4-alkyl-L-proline motif. (2022)
- Baraa Jadalla– UCT- The benefit of 4-alkyl-L-proline motif for biological activity of microbial metabolites with distinct modes of action (2022)
- Michaela Novotná FSUC- Regulation of gene expression of antibiotic resistance ABCF proteins and their role in the regulation of translation (2021)
- Michaela Plechatá UCT- Structural and functional diversity of bioactive specialized metabolites produced by Actinobacteria (2021)
- Lada Hanzlíková (Brázdová) UCT- Genome mining towards novel metabolites with 4-alkyl-L-proline moieties (2019)
- Magdalena Lenartová FSUC- Biosynthesis of pyrrolobenzodiazepines and related natural compounds(2015)- maternity leave
- Ludmila Veselá FSUC- Antibiotic resistance conferred by members of ARE subfamily of ABC proteins (2015)
Tereza Chlumská, FSUC- Characterization of a novel type 23S rRNA methyltransferase as a mechanism of macrolide resistance in Clostridioides difficile (2024)
Kateryna Trufan, FSUC- Mechanism of regulation of lincomycin biosynthesis by LmrC protein: role of ribosome-mediated antitermination (2024)
Lucie Šírová, FSUC- Mechanisms of resistance to pleuromutilins in Streptomyces coelicolor (2024)
- Emma Polomská UCT- Unraveling new bioactive metabolites with alkylproline motif through gene cluster expression and chemical structure elucidation (2023)
- Natalie Zárybnická UCT- Homologs of eukaryotic histone methyltranferases in the biosynthesis of bacterial metabolites: structure and function elucidation (2023)
- Jakub Musil UCT -Mechanism of gene expression regulation controlled by the ribosome-binding ABCF ATPase LmrC (2022)
- Lucie Korbová FSUC -The role of LmbF and CcbF proteins in the biosynthesis of the antibiotics lincomycin and celesticetin and their potential application in the biosynthesis of the hybrid antibiotic celin (2022)
| Name | Acquired degree/position in our lab | Current career (as of 2024) |
| Veronika Zachovalová | MSc. (2023) | Technician in Ghc Genetics |
| Kateřina Nováková | MSc. (2023) | Process Engineer- EXBIO- department of cells |
| Gioele Pecin | MSc. (2023) | Ph.D. student at Fundacion MEDINA, Spain |
| Eliška Mašková | MSc. (2023) | Process Engineer- EXBIO |
| Pamela Omena Petravicius | Ph.D. student | |
| Jakub Lenárt | Ph.D. (2022) | Microbiology analyst in Aeskulab |
| Monika Bartalová | MSc. (2021) | QC associate in SCTbio |
| Lukáš Kekrt | MSc. (2021) | Copywriter in HUSTA PR agency |
| Šimon Vobruba | Ph.D. (2021) | Researcher at the Institute of Organic Chemistry and Biochemistry |
| Bianka Micke | Bc. (2020) | Ph.D. student at Faculty of Science, Charles University in Prague |
| Bára Seidlová (Lisnerová) | MSc. (2020) | Office Leader & Clinical Trial Coordinator at Clinical Research Center |
| Petra Jirásková | Ph.D. (2020) | Laboratory specialist at Nachod hospital |
| Lukáš Cudlman | MSc. (2019) | Ph.D. student in analytical chemistry, Faculty of Science, Charles University & Institute of Organic Chemistry and Biochemistry |
| Jana Prášilová (Havlová) | MSc. (2018) | |
| Nikola Pinďáková | MSc. (2018) | Clinical research associate, Novo Nordisk, ICON Strategic Solutions |
| Barbora Těšínská | MSc (2018) | Clinical microbiology expert at Bulovka Hospital |
| Lucie Palanová (Růžičková) | MSc. (2017) | Lab manager at University of South Bohemia in České Budějovice |
| Vít Rynd | MSc. (2017) | Forensic organic chemistry expert in the Institute of Criminalistics, Police of the Czech Republic |
| Markéta Válková | MSc. (2017) | |
| Leona Zieglerová | MSc. (2015) | Quality assurance officer in Quinta-Analytika |
| Ludmila Veselá | MSc. (2015) | Junior Researcher at CEITEC, Masaryk University |
| Tomáš Kučera | Ph.D. (2013) | Senior head of strategic alliances and channel partners in Saphetor (VarSome), Barcelona, Spain |
| Dana Chytrá | MSc. (2012) | Laboratory specialist at SEQme |
| Tomáš Bakal | MSc. (2011) | Specialist in SCTbio |
| Marek Poĺan | MSc. (2011) | Senior regulatory affairs specialist in ICON plc |
| Yvona Smutná | MSc. RNDr. (2010) | Toxikologist at Regumed GmbH |
| Dana Ulanová | Ph.D. (2010) | Researcher and lecturer at Kochi University, Japan |
| Michaela Kroová | MSc. (2010) | |
| Klára Holá | Ph.D. (2008) | |
| Dominika Chalupská | MSc. (2008) | Researcher at the Institute of Organic Chemistry and Biochemistry |
| Lenka Sabová | MSc. (2008) | Microbiology expert in Citylab – clinical laboratories |
| Alexander Gakh | CSc. (2001) | Research assistant at Mayo Clinic, Rochester, USA |
| Jan Kadlec | MSc. (2000) | Researcher at Institut de biologie structurale (IBS) – CNRS, Grenoble, France |
| Zoia Stoycheva | CSc. (1999) | Assistant professor at University of Hawaii at Manoa, USA |
| Bojana Radojevic | Ph.D. student | Instrument sales specialist in Akoya Biosciences, Inc. , USA |
| Vladimir Vimberg | postdoc | NGS Specialist at SEQme |
| Eva Kutejová | PI | Director of the Institute of Molecular Biology, Slovak Academy of Sciences, Slovakia |
| Abdul Samad | postdoc | Researcher at the Institute of Microbiology |
| Juan David Guzman | postdoc | Senior Scientist in NewPath Bio GmbH, Vienna, Austria |
| Jan Kopecký | Ph.D., postdoc | Researcher at Crop Research Institute |
| Markéta Marečková | Ph.D., postdoc | Researcher and lecturer at Czech University of Life Sciences |
| Jitka Novotná | Ph.D., postdoc | Expert in State Health Institute (SZU) |
| Jana Veselá | technician | Protein facility specialist in DIANA Biotechnologies |
| Bich Nguyen Thi Ngoc | MSc. | |
| Jaroslav Spížek | lab leader, institute director | retired |
| Miloslav Klégr | technician | retired |
| Kamila Plháčková | technician | retired |
| Vendulka Jechová | technician | retired |
Institue of Microbiology
Institute of Microbiology, CAS
Vídeňská 1083, 142 20 Prague 4 - Krč
The Czech Republic
BIOCEV
Institute of Microbiology, CAS
Průmyslová 595, 252 50 Vestec
The Czech Republic
Contact Us
lab111@biomed.cas.cz
+420 241 062 371